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In a study by Ji et al., a novel group of β-amino pyrrole-2-carbonitrile analogs was developed as selective DPP-4 inhibitors, with compound 55 (Figure 7) identified as the most potent, exhibiting an IC 50 value of 0.01 µM
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Compelling evidence for SGLT2 inhibitors and GLP-1 receptor agonists as first-line therapy in patients with diabetes at very high/high cardiovascular risk
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